Publications

2012-13

McAvoy NC, Plevris JN, Hayes PC.   Human thrombin for the treatment of gastric and ectopic varices.    World J Gastroenterol. 2012 Nov 7;18(41):5912-7

Leithead JA, Ferguson JW, Hayes PC.  Modifiable patient factors are associated with the late decline in renal function following liver transplantation.  Clin Transplant. 2012 May-Jun;26(3):

Ramachandran P, Hayes PC.  Focusing on the patient: impact of new UK guidelines on treatment of chronic hepatitis C.  Expert Rev Gastroenterol Hepatol. 2012 Jun;6(3):259-61

Innes HA, Hutchinson SJ, Barclay S, Cadzow E, Dillon JF, Fraser A, Goldberg DJ, Mills PR, McDonald SA, Morris J, Stanley A, Hayes P; Hepatitis C Clinical Database Monitoring Committee.   Quantifying the fraction of cirrhosis attributable to alcohol among chronic hepatitis C virus patients: implications for treatment cost-effectiveness.  Hepatology. 2013 Feb;57(2):451-60

Craig DG, Lee P, Pryde EA, Walker SW, Beckett GJ, Hayes PC, Simpson KJ.    Elevated levels of the long pentraxin 3 in paracetamol-induced human acute liver injury.    Eur J Gastroenterol Hepatol. 2013 Mar;25(3):359-67

Lehwald N, Duhme C, Wildner M, Kuhn S, Fürst G, Forbes SJ, Jonas S, Robson SC, Knoefel WT, Schmelzle M, Esch JS. HGF and SDF-1-mediated mobilization of CD133(+) BMSC for hepatic regeneration following extensive liver resection. Liver Int.2013 May 2. doi: 10.1111/liv.12195. [Epub ahead of print]

Boulter L, Lu WY, Forbes SJ. Differentiation of progenitors in the liver: a matter of local choice. J Clin Invest. 2013 May 1;123(5):1867-73.

Bird TG, Lu WY, Boulter L, Gordon-Keylock S, Ridgway RA, Williams MJ, Taube J, Thomas JA, Wojtacha D, Gambardella A, Sansom OJ, Iredale JP, Forbes SJ. Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6542-7.

Ramachandran P, Pellicoro A, Vernon MA, Boulter L, Aucott RL, Ali A, Hartland SN, Snowdon VK, Cappon A, Gordon-Walker TT, Williams MJ, Dunbar DR, Manning JR, van Rooijen N, Fallowfield JA, Forbes SJ, Iredale JP. Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the  regression of murine liver fibrosis. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3186-95.

Stutchfield BM, Forbes SJ. Liver sinusoidal endothelial cells in disease--and for therapy? J Hepatol. 2013 Jan;58(1):178-80.

Boulter L, Govaere O, Bird TG, Radulescu S, Ramachandran P, Pellicoro A, Ridgway RA, Seo SS, Spee B, Van Rooijen N, Sansom OJ, Iredale JP, Lowell S, Roskams T, Forbes SJ. Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med. 2012 Mar 4;18(4):572-9.

Pellicoro A, Aucott RL, Ramachandran P, Robson AJ, Fallowfield JA, Snowdon VK, Hartland SN, Vernon M, Duffield JS, Benyon RC, Forbes SJ, Iredale JP. Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis. Hepatology. 2012 Jun;55(6):1965-75.

Forbes SJ, Newsome PN. New horizons for stem cell therapy in liver disease. J  Hepatol. 2012 Feb;56(2):496-9.

Falconer S, Powell JJ, Oniscu GC. When there is not plenty for everyone: options for reconstructing a suprahepatic vena cava injured during organ procurement. Liver Transpl. 2013 Mar;19(3):349-50.

Levitsky J, Oniscu GC. Meeting report of the International Liver Transplantation Society's 18th annual international congress: Hilton San Francisco Hotel, San Francisco, CA, May 16-19, 2012. Liver Transpl. 2013 Jan;19(1):27-35.

Devey LR, Richards JA, O'Connor RA, Borthwick G, Clay S, Howie AF, Wigmore SJ, Anderton SM, Howie SE. Ischemic preconditioning in the liver is independent of regulatory T cell activity. PLoS One. 2012;7(11):e49647.

Sanjay P, Watt DG, Wigmore SJ. Systematic review and meta-analysis of haemostatic and biliostatic efficacy of fibrin sealants in elective liver surgery. J Gastrointest Surg. 2013 Apr;17(4):829-36.

McNally SJ, Wigmore SJ. The Scottish Liver Transplant Unit: current and future perspectives. Scott Med J. 2011 Nov;56(4):223-6.

2011-12

O'Carroll RE, Ferguson E, Hayes PC, Shepherd L.  Increasing organ donation via anticipated regret (INORDAR): protocol for a randomised controlled trial.BMC Public Health. 2012 Mar 8;12:169.

Mpabanzi L, Deutz N, Hayes PC, Dejong CH, Olde Damink SW, Jalan R. Overnight glucose infusion suppresses renal ammoniagenesis and reduces hyperammonaemia induced by a simulated bleed in cirrhotic patients. AP & T 2012;35:921-928.

Krystallis C, Masterton GS, Hayes PC, Plevris JN.Update of endoscopy in liver disease: more than just treating varices.  World J Gastroenterol. 2012 Feb 7;18(5):401-11. Review.

Ramachandran P, Fraser A, Agarwal K, Austin A, Brown A, Foster GR, Fox R, Hayes PC, Leen C, Mills PR, Mutimer DJ, Ryder SD, Dillon JF.   UK consensus guidelines for the use of the protease inhibitors boceprevir and telaprevir in genotype 1 chronic hepatitis C infected patients.  Aliment Pharmacol Ther. 2012 Mar;35(6):647-62

Craig DG, Reid TW, Wright EC, Martin KG, Davidson JS, Hayes PC, Simpson KJ. The sequential organ failure assessment (SOFA) score is prognostically superior to the model for end-stage liver disease (MELD) and MELD variants following paracetamol (acetaminophen) overdose.  Aliment Pharmacol Ther. 2012 Mar;35(6):705-13. 

Craig DG, Bates CM, Davidson JS, Martin KG, Hayes PC, Simpson KJ.   Staggered overdose pattern and delay to hospital presentation are associated with adverse outcomes following paracetamol-induced hepatotoxicity.  Br J Clin Pharmacol. 2012 Feb;73(2):285-94. 

Leithead JA, Ferguson JW, Bates CM, Davidson JS, Simpson KJ, Hayes PC.  Chronic kidney disease after liver transplantation for acute liver failure is not associated with perioperative renal dysfunction.   Am J Transplant. 2011 Sep;11(9):1905-15. 

Craig DG, Lee P, Pryde EA, Masterton GS, Hayes PC, Simpson KJ.    Circulating apoptotic and necrotic cell death markers in patients with acute liver injury.  Liver Int. 2011 Sep;31(8):1127-36. 

Craig DG, Reid TW, Martin KG, Davidson JS, Hayes PC, Simpson KJ.    The systemic inflammatory response syndrome and sequential organ failure assessment scores are effective triage markers following paracetamol (acetaminophen) overdose. Aliment Pharmacol Ther. 2011 Jul;34(2):219-28. 

Dabos KJ, Whalen HR, Newsome PN, Parkinson JA, Henderson NC, Sadler IH, Hayes PC, Plevris JN.Impaired gluconeogenesis in a porcine model of paracetamol induced acute liver failure. World J Gastroenterol. 2011 Mar 21;17(11):1457-61.

Leithead JA, MacKenzie SM, Ferguson JW, Hayes PC.   Is estimated glomerular filtration rate superior to serum creatinine in predicting mortality on the waiting list for liver transplantation?  Transpl Int. 2011 May;24(5):482-8. 

Boulter L, Govaere O, Bird TG, Radulescu S, Ramachandran P, Pellicoro A,Ridgway RA, Seo SS, Spee B, Van Rooijen N, Sansom OJ, Iredale JP, Lowell S,Roskams T, Forbes SJ. Macrophage-derived Wnt opposes Notch signaling to specifyhepatic progenitor cell fate in chronic liver disease. Nat Med. 2012 Mar4;18(4):572-9.

Pellicoro A, Aucott RL, Ramachandran P, Robson AJ, Fallowfield JA, Snowdon VK,Hartland SN, Vernon M, Duffield JS, Benyon RC, Forbes SJ, Iredale JP. Elastinaccumulation is regulated at the level of degradation by macrophagemetalloelastase (MMP-12) during experimental liver fibrosis. Hepatology. 2011 Dec 27. doi: 10.1002/hep.25567. [Epub ahead of print] PubMed PMID: 22223197.

Forbes SJ, Newsome PN. New horizons for stem cell therapy in liver disease. J Hepatol. 2012 Feb;56(2):496-9.

Forbes SJ, Parola M. Liver fibrogenic cells. Best Pract Res ClinGastroenterol. 2011 Apr;25(2):207-17.

Schrader J, Gordon-Walker TT, Aucott RL, van Deemter M, Quaas A, Walsh S, Benten D, Forbes SJ, Wells RG, Iredale JP. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011 Apr;53(4):1192-205.

Thomas JA, Pope C, Wojtacha D, Robson AJ, Gordon-Walker TT, Hartland S, Ramachandran P, Van Deemter M, Hume DA, Iredale JP, Forbes SJ. Macrophage therapyfor murine liver fibrosis recruits host effector cells improving fibrosis, regeneration, and function. Hepatology. 2011 Jun;53(6):2003-15.
 
Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP. Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism. Stem Cell Res. 2011 Mar;6(2):92-102.

Payne CM, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine CN, Forbes SJ, Iredale JP, Newsome PN, Hay DC. Persistence of functional hepatocyte-like cells in immune-compromised mice. Liver Int. 2011 Feb;31(2):254-62

Kallis YN, Robson AJ, Fallowfield JA, Thomas HC, Alison MR, Wright NA, Goldin RD, Iredale JP, Forbes SJ. Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response. Gut. 2011 Apr;60(4):525-33.

McNally SJ, Wigmore SJ. The Scottish Liver Transplant Unit: current and future perspectives. Scott Med J. 2011 Nov;56(4):223-6. PubMed PMID: 22089045.

Stutchfield BM, Simpson KJ, Wigmore SJ. Is there a role for extracorporeal liver support as a bridge to liver transplantation in acute liver failure? Transplantation. 2011 Oct 27;92(8):e44-5. PubMed PMID: 21989274.

Wigmore SJ. Can serotonin agonists unlock age-dependent failure of liver regeneration? J Hepatol. 2011 Dec;55(6):1455-6.

Matas AJ, Adair A, Wigmore SJ. Paid organ donation. Ann R CollSurg Engl. 2011 Apr;93(3):188-92.

Stutchfield BM, Simpson K, Wigmore SJ. Systematic review and meta-analysis of  survival following extracorporeal liver support. Br J Surg. 2011 May;98(5):623-31.

King A, Masterton G, Gunson B, Olliff S, Redhead D, Mangat K, Oniscu G, Hayes P, Tripathi D.A case-controlled study of the safety and efficacy of transjugular intrahepatic portosystemic shunts after liver transplantation.Liver Transpl. 2011 Jul;17(7):771-8.

Castillo-Suescun F, Oniscu GC, Hidalgo E.Hemodynamic consequences of spontaneous splenorenal shunts in deceased donor liver transplantation.Liver Transpl. 2011 Aug;17(8):891-5.

Adair A, Brooke-Smith ME, Akyol M, Powell JJ. Maximizing use of marginal liver grafts for transplantation: a case report of absent donor extrahepatic portal vein. Transplantation. 2011 Mar 27;91(6):e42-3.

Barber K, Madden S, Allen J, Collett D, Neuberger J, Gimson A; United Kingdom Liver Transplant Selection and Allocation Working Party. Elective liver transplant list mortality: development of a United Kingdom end-stage liver disease score. Transplantation. 2011 Aug 27;92(4):469-76.

Previous Publications

Cookson DT, Zaman Z, Gordon-Smith J, Ireland HM, Hayes PC. Management of transjugular intrahepatic portosystemic shunt (TIPS)-associated refractory hepatic encephalopathy by shunt reduction using the parallel technique: outcomes of a retrospective case series. Cardiovasc Intervent Radiol. 2011 Feb;34(1):92-9.
Epub 2010 Nov 6. PubMed PMID: 21057793.

Newsome PN, Henderson NC, Nelson LJ, Dabos C, Filippi C, Bellamy C, Howie F, Clutton RE, King T, Lee A, Hayes PC, Plevris JN. Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure. BMC Gastroenterol. 2010 Mar 30;10:34.
PubMed PMID: 20353598; PubMed Central PMCID: PMC2856523.

McGregor LM, Swanson V, Hayes PC, Forsythe JR, O'Carroll RE. Considering adult living donor liver transplantation: a qualitative study of patients and their potential donors. Psychol Health. 2010 Jul;25(6):751-66. PubMed PMID: 20204957.

Craig DG, Reid TW, Martin KG, Davidson JS, Hayes PC, Simpson KJ. The systemic inflammatory response syndrome and sequential organ failure assessment scores are effective triage markers following paracetamol (acetaminophen) overdose. Aliment Pharmacol Ther. 2011 May 10. doi: 10.1111/j.1365-2036.2011.04687.x.
[Epub ahead of print]

Gilchrist ES, Plevris JN. Bone marrow-derived stem cells in liver repair: 10 years down the line. Liver Transpl. 2010 Feb;16(2):118-29. Review.
PubMed PMID: 20104479.

Blackstock M, McKeown DW, Ray DC. Controlled organ donation after cardiac death: potential donors in the emergency department. Transplantation. 2010 May 15;89(9):1149-53.
PubMed PMID: 20130495.

Sharma R, Greenhough S, Medine CN, Hay DC. Three-dimensional culture of human embryonic stem cell derived hepatic endoderm and its role in bioartificial liver construction. J Biomed Biotechnol. 2010;2010:236147. Epub 2010 Feb 8. Review.
PubMed PMID: 20169088; PubMed Central PMCID: PMC2821762.

Craig DG, Ford AC, Hayes PC, Simpson KJ. Systematic review: prognostic tests of paracetamol-induced acute liver failure. Aliment Pharmacol Ther. 2010 May;31(10):1064-76. Epub 2010 Feb 24. Review.
PubMed PMID: 20180786.

Wigmore SJ. Similar liver transplantation survival with selected cardiac death donors and brain death donors (Br J Surg 2010; 97: 744-753). Br J Surg. 2010 May;97(5):753.
PubMed PMID: 20393980.

Oniscu GC, Wigmore SJ. Increasing donor body weight to prevent small-for-size syndrome in living donor liver transplantation. World J Surg. 2010 Oct;34(10):2409-10.
PubMed PMID: 20533035.

Stutchfield BM, Forbes SJ, Wigmore SJ. Prospects for stem cell transplantation in the treatment of hepatic disease. Liver Transpl. 2010 Jul;16(7):827-36. Review.
PubMed PMID: 20583084.

Dalakas E, Newsome PN, Boyle S, Brown R, Pryde A, McCall S, Hayes PC, Bickmore  WA, Harrison DJ, Plevris JN. Bone marrow stem cells contribute to alcohol liver fibrosis in humans. Stem Cells Dev. 2010 Sep;19(9):1417-25. PubMed PMID: 20025456.

Khan LR, Oniscu GC, Powell JJ. Long-term outcome following liver transplantation for paracetamol overdose. Transpl Int. 2010 May 1;23(5):524-9.
Epub 2009 Nov 25. PubMed PMID: 20002359.

Vass DG, Hughes J, Marson LP. Restorative and rejection-associated lymphangiogenesis after renal transplantation: friend or foe? Transplantation. 2009 Dec 15;88(11):1237-9. Review.
PubMed PMID: 19996921.

Stutchfield BM, Rashid S, Forbes SJ, Wigmore SJ. Practical barriers to delivering autologous bone marrow stem cell therapy as an adjunct to liver resection. Stem Cells Dev. 2010 Feb;19(2):155-62. Review.
PubMed PMID: 19954303.

Craig DG, Lee A, Hayes PC, Simpson KJ. Review article: the current management of acute liver failure. Aliment Pharmacol Ther. 2010 Feb 1;31(3):345-58.
Epub 2009 Oct 21.
Review. PubMed PMID: 19845566.

Wigmore SJ. Increase in future remnant liver function after preoperative portal vein embolization (Br J Surg 2011; 98: 825-834). Br J Surg. 2011 Jun;98(6):835. doi: 10.1002/bjs.7492.
PubMed PMID: 21523698.

Castillo-Suescun F, Oniscu G, Hidalgo E. Hemodynamic consequences of spontaneous spleno-renal shunts in deceased donor liver transplantation. Liver Transpl. 2011 Mar 21. doi: 10.1002/lt.22304. [Epub ahead of print] PubMed PMID: 21425432.

Leithead JA, Mackenzie SM, Ferguson JW, Hayes PC. Is estimated glomerular filtration rate superior to serum creatinine in predicting mortality on the waiting list for liver transplantation? Transpl Int. 2011 May;24(5):482-8. doi:
10.1111/j.1432-2277.2011.01231.x. Epub 2011 Mar 1.
PubMed PMID: 21362061.

Craig DG, Bates CM, Davidson JS, Martin KG, Hayes PC, Simpson KJ. Overdose pattern and outcome in paracetamol-induced acute severe hepatotoxicity. Br J Clin Pharmacol. 2011 Feb;71(2):273-82. doi: 10.1111/j.1365-2125.2010.03819.x.
PubMed PMID: 21219409; PubMed Central PMCID: PMC3040549.

Richards JA, Wigmore SJ, Devey LR. Heme oxygenase system in hepatic ischemia-reperfusion injury. World J Gastroenterol. 2010 Dec 28;16(48):6068-78.
PubMed PMID: 21182221; PubMed Central PMCID: PMC3012573.

Potts SG. Transplant psychiatry. J R Coll Physicians Edinb. 2009 Dec;39(4):331-6.
PubMed PMID: 21152475.

Payne CM, Samuel K, Pryde A, King J, Brownstein D, Schrader J, Medine CN, Forbes SJ, Iredale JP, Newsome PN, Hay DC. Persistence of functional hepatocyte-like cells in immune-compromised mice. Liver Int. 2011
Feb;31(2):254-62. doi: 10.1111/j.1478-3231.2010.02414.x.
Epub 2010 Dec 10. PubMed PMID: 21143581.

Last Reviewed: 15/10/2013